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प्रश्न
The first clinical gene therapy was done for the treatment of ________.
पर्याय
AIDS
Cancer
Cystic fibrosis
SCID
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उत्तर
The first clinical gene therapy was done for the treatment of SCID.
Explanation:
The first clinical gene therapy was performed to treat SCID (severe combination immune deficiency) caused by an ADA deficiency.
APPEARS IN
संबंधित प्रश्न
Expand the Given and mention one application of each:
PCR
State the role of C-peptide in human insulin.
State the cause of ADA deficiency in humans.Mention a possible cure for an ADA deficiency patient.
What is gene therapy? Name the first clinical case in which it was used.
Why does Bt toxin not kill the bacterium that produces it, but kill the insect that ingests it?
Write any two biochemical/molecular diagonostic procedures for early detection of viral infection. Explain the principle of any one of them.
Describe the role of primers.
How many amino acids are arranged in the two chains of Insulin?
Which one of the following statements is true regarding DNA polymerase used in PCR?
ELISA is mainly used for ____________.
How is the amplification of a gene sample of interest carried out using PCR?
What are recombinant vaccines? Explain the types.
Explain how recombinant Insulin can be produced.
ADA is an enzyme which is deficient in a genetic disorder SCID. What is the full form of ADA?
What is a recombinant DNA vaccine? Give two examples.
The diagram given below represents the schematic structure of proinsulin, which undergoes certain modifications before it becomes a fully functional insulin.
Study the diagram carefully and answer the questions that follow:
- State the change the proinsulin undergoes to become fully functional.
- Name the modern scientific technique used for the production of human insulin.
- How are the two polypeptide chains of the fully functional insulin held together?
In the recombinant production of humulin using Escherichia coli, which plasmid vector and bacterial gene are fused with the human insulin A and B chain sequences?
Severe Combined Immunodeficiency Disease (SCID) caused by adenosine deaminase (ADA) deficiency arises due to which pathological mechanism?
