Advertisements
Advertisements
Question
Write the equations involved in the following reactions : Williamson synthesis
Advertisements
Solution 1
Solution 2
Williamson synthesis: It involves the treatment of an alkyl halide with a suitable sodium alkoxide. The sodium alkoxide needed for the purpose is prepared by the action of sodium on a suitable alcohol. The reaction invlolves the nucleophillic displacement (substitution) of the halide ion from the alkyl halide by the alkoxide ion by SN2 mechanism.
R-OH +2Na → 2R’-O-Na+ + H2
R’-O-Na+ + R-X → R’-O-R +Na+ X
Ether
The second reaction is the substitution nucleophillic bimolecular (SN2) reaction.
For example:
APPEARS IN
RELATED QUESTIONS
How do you convert the following :
Phenol to anisole
Write the name of the reagent and the equation for the preparation of the following ether by Williamson’s synthesis:
2-Methoxy-2-methylpropane
Account for the following :
t-butyl chloride on heating with sodium methoxide gives 2-methylpropene instead of t-butyl methyl ether.
Dehydration of alcohol to ethers is catalysed by:
Write the name of the reaction, structure and IUPAC name of the product formed when:
\[\ce{CH3CH2CH(CH3)CH(CH3) ONa}\] reacts with \[\ce{C2H5Br}\]
Write the name of reagent and equation for the preparation of the following ethers by Williamson’s synthesis:
2-Methoxy-2-methylpropane
Write the name of the reagent and equation for the preparation of the following ether by Williamson’s synthesis:
2-Methoxy-2-methylpropane
Identify the product(s) is/are formed when 1-methoxy propane is heated with excess HI. Name the mechanism involved in the reaction.
Give the structure and IUPAC name of the metamers of 2-methoxy propane.
Write the name of reagent and equation for the preparation of the following ether by Williamson’s synthesis:
2-Methoxy-2-methylpropane
