Question

Why is controlled crossing not possible in human pedigree studies?

Options

• Pedigree analysis was invented before controlled crosses were discovered

• Humans have too many chromosomes for analysis

• Ethical and social barriers prevent planned human matings

• The human genome is too complex to inherit traits

Answer 1

Controlled crosses are not possible in humans due to ethical and social barriers that prevent planned matings. This is a fundamental reason why pedigree analysis is used as an alternative method to study human inheritance patterns, similar to the controlled crosses performed with pea plants.