Question

Which of the following mutations would be most likely to have a harmful effect on an organism?

Options

• A single base insertion near the start of the coding sequence.

• A base-pair substitution.

• A single-base deletion near the middle of an intron.

• A single base deletion close to the end of the coding sequence.

Answer 1

A single base insertion near the start of the coding sequence.

Explanation:

This statement is incorrect because introns (non-coding regions) are the segments that are excised and removed during RNA splicing, not exons. Exons are the essential coding sequences that are joined together to form the mature mRNA molecule, which then exits the nucleus to be translated into protein