Question

Which of the following is the first step in the methodology of the Human Genome Project?

Options

• Isolation of DNA from cells

• Breaking DNA into smaller fragments

• Sequencing the DNA fragments

• Cloning fragments into suitable vectors

Answer 1

According to the methodology of the Human Genome Project, the first step was the isolation of DNA from cells. This foundational step was necessary to obtain the genetic material that would subsequently be fragmented, cloned, sequenced, and analyzed through the remaining steps of the project.