Question

What vectors were used for cloning and maintaining DNA fragments in the Human Genome Project?

Options

• Liposomes and micelles

• Plasmids and cosmids only

• BACs and YACs

• Viruses and transposons

Answer 1

BACs (Bacterial Artificial Chromosomes) and YACs (Yeast Artificial Chromosomes) were the suitable vectors used for cloning DNA fragments in the Human Genome Project. These vectors were chosen because they could maintain and allow study of large DNA fragments, which was essential for managing the vast genetic information generated during the project.