Question

One of Chargaff’s rules states that:

Options

• A + T = G + C

• A + G = T + C

• A = G, T = C

• A = C, T = G

Answer 1

A + G = T + C

Explanation:

This rule is based on the principle of molecular equivalence in double-stranded DNA. Since Adenine (A) always pairs with Thymine (T) and Guanine (G) always pairs with Cytosine (C), the total amount of purines (A + G) must always equal the total amount of pyrimidines (T + C).