Question

Monoclonal antibodies are ______.

Options

• produced by clones formed from memory cells

• used to produce large quantities of interferon

• produced by cultures of hybridoma cells

• produced by clones of T-cells fused with tumour cells

Answer 1

Monoclonal antibodies are produced by cultures of hybridoma cells.

Explanation:

Monoclonal antibodies are produced using hybridoma technology, where antibody-producing lymphocyte cells (usually from the spleen of a mouse immunized with the antigen) are fused with myeloma (tumor) cells to form hybridoma cells. These hybridomas can be cultured to produce large quantities of a single type (monoclonal) of antibody with defined specificity. This method enables continuous antibody production in culture.