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Question
Label the diagram and write down the detail of concept in your word.

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Solution
- structure of Endoplasmic Reticulum:
- Endoplasmic reticulum is a network present within the cytosol.
- It is present in all eukaryotic cells except ova and mature red blood corpuscles.
- Under the electron microscope, it appears like network of membranous tubules and sacs called cisternae.
- This network of ER divides the cytoplasm in two parts viz. one within the lumen of ER called laminal cytoplasm and non-laminal cytoplasm that lies outside ER.
- Membrane of ER is continuous with nuclear envelope at one end and extends till cell membrane. It thus acts as intracellular supporting framework and helps in maintaining position of various cell organelles in the cytoplasm.
- Depending upon the presence or absence of ribosomes, endoplasmic reticulum is called rough endoplasmic reticulum (RER) or smooth endoplasmic reticulum (SER) respectively.
- Smooth endoplasmic reticulum (SER):
- Depending on cell type, it helps in synthesis of lipids for e.g. Steroid secreting cells of cortical region of adrenal gland, testes and ovaries.
- Smooth endoplasmic reticulum plays a role in detoxification in the liver and storage of calcium ions (muscle cells).
- Rough Endoplasmic Reticulum (RER):
- Rough ER is primarily involved in protein synthesis. For e.g. Pancreatic cells synthesize the protein insulin in the ER.
- These proteins are secreted by ribosomes attached to rough ER and are called secretory proteins. These proteins get wrapped in membrane that buds off from transitional region of ER. Such membrane bound proteins depart from ER as transport vesicles.
- Rough ER is also involved in formation of membrane for the cell. The ER membrane grows in place by addition of membrane proteins and phospholipids to its own membrane. Portions of this expanded membrane are transferred to other components of endomembrane system.
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