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Question
In DNA replication, the Okazaki fragments on the lagging strand are joined together by ______.
Options
DNA ligase
DNA polymerase
primase
helicase
MCQ
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Solution
In DNA replication, the Okazaki fragments on the lagging strand are joined together by DNA ligase.
Explanation:
On the lagging strand, DNA is synthesised as short Okazaki fragments; after RNA primers are removed and the gaps are filled, DNA ligase seals the remaining nicks by forming the phosphodiester bonds that join the fragments into a continuous strand.
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