Question

In a nucleosome, the DNA is wrapped around ______.

Options

• polymerase molecules

• ribosomes

• histones

• nucleolus

Answer 1

In a nucleosome, the DNA is wrapped around histones.

Explanation:

In a nucleosome, the DNA is wrapped around a core of histone proteins. This structure serves as the fundamental unit of DNA packaging in eukaryotic cells, helping to condense about six feet of DNA into the tiny confines of the cell nucleus. The core consists of a histone octamer, a group of eight histone molecules (two each of H2A, H2B, H3, and H4), around which approximately 147 base pairs of DNA are wound about 1.65 times. Because DNA is negatively charged and histones are positively charged, they bind together very tightly to form a “beads-on-a-string” arrangement.