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Question
How does initiation of the translation process occur in prokaryotes? Explain.
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Solution
For initiation, the ribosome binds to the mRNA at the start codon (AUG) that is recognised only by the initiator tRNA. The ribosome proceeds to the elongation phase of protein synthesis. During this stage, complexes composed of an amino acid linked to tRNA, sequentially bind to the appropriate codon in mRNA by forming complementary base pairs with the tRNA anticodon. The ribosome moves from codon to codon along the mRNA. Amino acids are added one by one, translated into Polypeptide sequences dictated by DNA and represented by mRNA. At the end, a release factor binds to the stop codon, terminating translation and releasing the complete polypeptide from the ribosome.
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RELATED QUESTIONS
List two essential roles of ribosomes during translation.
The translation termination triplet is ______.
During translation, activated amino acids get linked to tRNA. This process is commonly called as ______.
Which of the following life processes is evolved around RNA?
Which of the following statements is correct regarding ribosomes?
Which of the following are correct statements for a tRNA molecule?
- It is an adapter molecule.
- Previously called sRNA (soluble RNA)
- tRNA has a codon loop that has bases complementary to the code,
- it also has an amino acid accepter end to which it binds to amino acids.
- It is non-specific for each amino acid.
Aminoacylation of tRNA also known as ______.
(a) Identify the polarity of x to x’ in the diagram below and mention how many more amino acids are expected to be added to this polypeptide chain.

(b) Mention the codon and anticodon for alanine.
(c) Why are some untranslated sequences of bases seen in mRNA coding for a polypeptide? Where exactly are they present on mRNA?
Where are the untranslated regions located on mRNA and why?
Codon on mRNA and anticodon on tRNA are ______.
