Question

Explain what happens in the RBCs of the humans when Plasmodium gains entry into them. How does the human body gets affected?

Answer 1

Plasmodium enters the human body as sporozoites (infectious form) through the bite of infected female
Anopheles mosquito. The parasites initially multiply within the liver cells and then attack the red blood cells (RBCs) resulting in their rupture. The rupture of RBCs is associated with release of a toxic substance, haemozoin, which is responsible for the chill and high fever recurring every three to four days.