Advertisements
Advertisements
Question
Explain the formation of a nucleosome.
Advertisements
Solution
Komberg proposed a model for the nucleosome, in which 2 molecules of the four histone proteins H2A, H2B, H3, and H4 are organized to form a unit of eight molecules called histone octamere.
The negatively charged DNA is wrapped around the positively charged histone octamere to form a structure called a nucleosome. A typical nucleosome contains 200 bp of DNA helix. The histone octameres are in close contact and DNA is coiled on the outside of the nucleosome.
Nucleosome
RELATED QUESTIONS
How are the following formed and involved in DNA packaging in a nucleus of a cell?
(ii) Nucleosome
(iii) Chromatin
In an octamer of the nucleosome, core DNA consists of ______ base pairs.
Very Short Answer Question:
Which are the nucleosomal 'core' histones?
Write a note on the packaging of DNA in prokaryotes.
The length of DNA segment having 44 base pairs is ______
Histone proteins are ______.
Read the following and answer from given below:
In prokaryotes, DNA is circular and present in the cytoplasm but in eukaryotes, DNA is linear and mainly confined to the nucleus. DNA or deoxyribonucleic acid is a long polymer of nucleotides. In 1953, the first correct double-helical structure of DNA was worked out by Watson and Crick. Based on the X-ray diffraction data produced by Maurice Wilkins and Rosalind Franklin. It is composed of three components, i.e., A phosphate group, a deoxyribose sugar, and a nitrogenous base. Different forms of DNA are B-DNA, Z-DNA, A-DNA, C-DNA, and D-DNA.
The double chain of B-DNA is coiled in a helical fashion. The spiral twisting of the B-DNA duplex produces ______
Which one of the following cell organelle is considered as ‘Cell within a cell’?
______ are the amino acids of histones.
What do the 'beads on strings' structure of DNA packaging represent?
