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Explain the formation of a nucleosome.

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प्रश्न

Explain the formation of a nucleosome.

संक्षेप में उत्तर
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उत्तर

Komberg proposed a model for the nucleosome, in which 2 molecules of the four histone proteins H2A, H2B, H3, and H4 are organized to form a unit of eight molecules called histone octamere.

The negatively charged DNA is wrapped around the positively charged histone octamere to form a structure called a nucleosome. A typical nucleosome contains 200 bp of DNA helix. The histone octameres are in close contact and DNA is coiled on the outside of the nucleosome.

 

Nucleosome

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अध्याय 5: Molecular Genetics - Evaluation [पृष्ठ ८६]

APPEARS IN

सामाचीर कलवी Biology (Zoology) [English] Class 12 TN Board
अध्याय 5 Molecular Genetics
Evaluation | Q 34. | पृष्ठ ८६
सामाचीर कलवी Biology (Zoology) [English] Class 12 TN Board
अध्याय 5 Molecular Genetics
Evaluation | Q 34. | पृष्ठ ८९

संबंधित प्रश्न

The number of adenine molecules in a given DNA segment is 25 and the number of cytosine molecules is 45, the total number of nucleotides in the segment is _______________.


Very Short Answer Question:

Which are the nucleosomal 'core' histones?


The octamer of histone protein is made of ______.


Which of the following is correct about mature RNA in eukaryotes?


Read the following and answer from given below:

In prokaryotes, DNA is circular and present in the cytoplasm but in eukaryotes, DNA is linear and mainly confined to the nucleus. DNA or deoxyribonucleic acid is a long polymer of nucleotides. In 1953, the first correct double-helical structure of DNA was worked out by Watson and Crick. Based on the X-ray diffraction data produced by Maurice Wilkins and Rosalind Franklin. It is composed of three components, i.e., A phosphate group, a deoxyribose sugar, and a nitrogenous base. Different forms of DNA are B-DNA, Z-DNA, A-DNA, C-DNA, and D-DNA.

The double chain of B-DNA is coiled in a helical fashion. The spiral twisting of the B-DNA duplex produces ______ 


Which process occurs in the regulation of gene expression in prokaryotes but does not occur in the regulation of gene expression in eukaryotes?


Which of the following amino acid residues will constitute the histone core?


What do the 'beads on strings' structure of DNA packaging represent?


In the prokaryotic DNA compaction pathway, what is the diameter of relaxed circular DNA?


What is the diameter of the nucleosome fibre (beads-on-string structure)?


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