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Question
Explain the following process:
Depolarisation of the membrane of a nerve fibre.
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Solution
- Depolarization of a nerve fibre membrane occurs when the activation gates of Na channels open while the K channels stay closed. Na+ rushes into the axon.
- The input of sodium ions produces depolarization (polarity reversal) of the neuronal membrane, making the contents of the nerve fibres electropositive compared to the extracellular fluid.
- Na+ starts entering the axoplasm rapidly, and as a result, depolarization of the nerve fibre starts. As a result of depolarization, a positive electrical charge is established on the inner surface of the neurilema and a negative electrical charge on the outer surface. This state is opposite the resting state.
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