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Question
Discuss with your teacher and find out how to distinguish between plasmid DNA and chromosomal DNA.
Distinguish Between
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Solution
| Sr. No. | Feature | Plasmid DNA | Chromosomal DNA |
| 1. | Location | Present in addition to chromosomal DNA, mostly in bacteria (accessory DNA) | Part of the normal chromosome in the cell |
| 2. | Size | Small molecule | Large molecule |
| 3. | Molecular Weight | Low molecular weight | Very high molecular weight |
| 4. | Replication | Capable of independent replication | Replicates with the cell's chromosomal DNA |
| 5. | Function | Often carries accessory genes (e.g., antibiotic resistance) | Carries essential genetic information for cell's life and function |
| 6. | Structure | Usually circular | Usually linear (in eukaryotes), circular in prokaryotes, but much larger and more complex |
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