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Question
Differentiate between the following:
Primary and Secondary lymphoid organs
Distinguish Between
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Solution
| Basis of Difference | Primary lymphoid organs | Secondary lymphoid organs |
|---|---|---|
| Definition | Sites of origin and proliferation (maturation) of lymphocytes. | Sites of interaction of lymphocytes with the antigen. |
| Function | Immature B and T lymphocytes mature and differentiate into antigen-sensitive lymphocytes. | Mature lymphocytes proliferate and differentiate into effector cells in response to specific antigens. |
| Examples | Bone marrow and thymus. | Lymph nodes, spleen, Peyer's patches, appendix, tonsils, MALT. |
| Microenvironment | Provide the microenvironment for development of B and T cells. | Provide the site for activation and action of lymphocytes. |
| Migration | Lymphocytes formed here migrate to secondary lymphoid organs. | Lymphocytes reach here via the circulatory system. |
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