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Question
Differentiate between the following:
Autograft and allograft
Distinguish Between
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Solution
| Basis of Difference | Autograft | Allograft |
|---|---|---|
| Definition | Transplant in which one's own tissue is grafted to another part of the same body. | Transplant between individuals of the same species but with different MHC/HLA. |
| Donor and recipient | The donor and recipient are the same individual. | The donor and recipient are different individuals of the same species. |
| Success rate | Most successful transplants (no immune rejection). | Success depends on the degree of matching of HLA proteins. |
| Rejection | No rejection, hence no immunosuppressants needed. | Rejection may occur, so immunosuppressive drugs like cyclosporin A are given. |
| Example | Skin grafted from one part of the body to another part during surgery. | Kidney transplant from a sibling or an unrelated donor. |
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