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Question
Answer the following question.
The RBC surface normally shows glycoprotein molecules. When determining blood group do they play any role?
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Solution
- Glycoproteins are protein molecules modified within the Golgi complex by having a short sugar chain (polysaccharide) attached to them.
- The polysaccharide part of glycoproteins located on the surfaces of red blood cells acts as the antigen responsible for determining the blood group of an individual.
- Different polysaccharide part of glycoproteins act as different type of antigens that determine the blood groups.
- Four types of blood groups A, B, AB, and O are recognized on the basis of presence or absence of these antigens
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