Question

A dinucleotide is formed by linking two nucleotides together. The bond formed between them is:

Options

• A 3′–5′ phosphodiester bond

• An N-glycosidic bond

• A hydrogen bond

• Two separate phosphoester bonds

Answer 1

When two nucleotides join to form a dinucleotide, the phosphate group of one nucleotide forms a single 3′–5′ phosphodiester bond with the 3′-OH group of the adjacent nucleotide. This is the same type of bond that links all nucleotides in a polynucleotide chain.