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प्रश्न
Answer the following question.
List the two methodologies which were involved in the human genome project. Mention how they were used.
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उत्तर
2 Methodologies of HGP :
- Expressed Sequence Tags (EST's):
This method focusses on identifying all the genes that are expressed as RNA. - Sequence Annotation:
It is an approach of simply sequencing the whole set of the genome that contains all the coding and non-coding sequences, and later assigning different regions in the sequence with functions.
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संबंधित प्रश्न
What do ‘Y’ and ‘B’ stand for in ‘YAC’ and ‘BAC’ used in the Human Genome Project (HGP)? Mention their role in the project.
Briefly describe the following:
Bioinformatics
The pairing of homologous chromosomes is call______
(a) crossing over
(b) terminalization
(c) synapsis
(d) bivalent
Define ‘genomics’. Give any ‘two’ applications of it.
Write any six salient features of the human genome as drawn from the human genome project.
Identify the main aims of Human Genome Project.
I. Taking care of the legal, ethical and social issues which may arise from the project.
II. Transfer of the related technologies to the private sectors, such as industries.
III. To develop tools and techniques for analysis of the data.
IV. To store the information collected from the project in databases.
V. Mapping the entire human genome at the level of nucleotide sequences.
A colourblind girl is rare because she will be born only when ______.
The total number of genes in humans is far less (< 25,000) than the previous estimate (upto 1,40,000 gene). Comment.
Give an account of the methods used in sequencing the human genome.
Which two major U.S. organizations coordinated the Human Genome Project?
