Advertisements
Advertisements
प्रश्न
Explain enzyme – replacement therapy to treat adenosine deaminase deficiency. Mention two disadvantages of this procedure.
Advertisements
उत्तर
Adenosine deaminase (ADA) deficiency is a genetic disorder. In this disorder, the gene coding for the enzyme ADA gets deleted leading to deficiency of ADA and problems in the immune system. ADA deficiency in patients can be treated by enzyme replacement therapy. In this treatment, patients are regularly injected with the functional ADA enzyme.
Disadvantages of this process:
(i) It does not eradicate the disease.
(ii) Requirement of repeated doses of the enzyme makes it expensive.
APPEARS IN
संबंधित प्रश्न
Diagrammatically represent the experimental steps in cloning and expressing an human gene (say the gene for growth hormone) into a bacterium like E. coli?
State the cause of ADA deficiency in humans.Mention a possible cure for an ADA deficiency patient.
Answer the following question.
Describe the roles of heat, primers, and the bacterium Thermus aquaticus in the process of PCR.
How many amino acids are arranged in the two chains of Insulin?
What is genetically engineered Insulin?
ELISA technique is based on the principles of antigen-antibody interaction. Can this technique be used in the molecular diagnosis of a genetic disorder, such as phenylketonuria?
PCR is a useful tool for early diagnosis of an Infectious disease. Elaborate.
Now a days it is possible to detect the mutated gene causing cancer by allowing a radioactive probe to hybridize its complimentary DNA in a clone of cells, followed by its detection using autoradiography because ______
Define Antigen and Antibody. Name any two diagnostic kits based upon them.
The diagram given below represents the schematic structure of proinsulin, which undergoes certain modifications before it becomes a fully functional insulin.
Study the diagram carefully and answer the questions that follow:
- State the change the proinsulin undergoes to become fully functional.
- Name the modern scientific technique used for the production of human insulin.
- How are the two polypeptide chains of the fully functional insulin held together?
