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प्रश्न
Explain enzyme – replacement therapy to treat adenosine deaminase deficiency. Mention two disadvantages of this procedure.
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उत्तर
Adenosine deaminase (ADA) deficiency is a genetic disorder. In this disorder, the gene coding for the enzyme ADA gets deleted leading to deficiency of ADA and problems in the immune system. ADA deficiency in patients can be treated by enzyme replacement therapy. In this treatment, patients are regularly injected with the functional ADA enzyme.
Disadvantages of this process:
(i) It does not eradicate the disease.
(ii) Requirement of repeated doses of the enzyme makes it expensive.
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संबंधित प्रश्न
Diagrammatically represent the experimental steps in cloning and expressing an human gene (say the gene for growth hormone) into a bacterium like E. coli?
Describe the steps that are followed during secondary treatment of sewage.
PCR proceeds in three distinct steps governed by temperature, they are in order of ____________.
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A patient is suffering from ADA deficiency. Can he be cured? How?
List the disadvantages of insulin obtained from the pancreas of slaughtered cows and pigs:
List the advantages of recombinant insulin.
