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Question
Write a note on the antigens-antibody complex.
Answer in Brief
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Solution
- Each antibody is specific for a particular antigen.
- Combining sites of antigen, called antigenic determinants (epitopes) react with the corresponding antigen-binding sites of antibodies called paratopes.
- The antigen-binding sites (paratopes) are located on the variable regions of the antibody.
- Small variations in the variable regions make each antibody highly specific for a particular antigen.
- The variable region enables the antibody to recognize the specific antigen and bind to a specific antigen in a lock and key manner forming an antigen-antibody complex.
Formation of antigen-antibody complex
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