Question

Why is osteoporosis of ageing people connected with hormones?

Answer 1

Osteoporosis in ageing individuals is closely linked to hormonal imbalances that disrupt normal bone remodeling. With increasing age, declining levels of sex hormones like oestrogen in postmenopausal females and testosterone in males accelerate bone calcium loss and reduce bone mineral density. Additionally, elevated levels of glucocorticoids such as cortisol cause bone breakdown, while reduced calcitonin activity impairs calcium absorption into skeletal tissues. Consequently, bones become progressively thin, porous, fragile, and highly prone to fractures.