Question

Which transgenic animal application involves testing the safety of biological preparations before human use?

Options

• Vaccine safety testing using transgenic mice

• Enhancement of disease resistance in aquaculture

• Production of therapeutic human proteins in milk

• Improvement of meat and wool production in agricultural animals

Answer 1

Transgenic mice are specifically used to test the safety of vaccines before they are administered to humans. This application is critical in pharmaceutical development, as it allows researchers to assess potential adverse effects and immune responses in a controlled animal model before human trials. The polio vaccine is a notable example of a vaccine tested using transgenic mice.