Question

Which sex chromosome abnormality involves a monosomy?

Options

• Neither syndrome involves monosomy

• Both Klinefelter's and Turner's syndromes

• Klinefelter's syndrome (47, XXY)

• Turner's syndrome (45, XO)

Answer 1

Turner's syndrome (45, XO) is a monosomy of sex chromosomes, meaning there is only one sex chromosome instead of the normal two. In contrast, Klinefelter's syndrome (47, XXY) is a trisomy, involving three sex chromosomes instead of two.