Question

Which scientist developed a method for synthesizing RNA molecules with repeated known nucleotide sequences to help decipher the genetic code?

Options

• Severo Ochoa

• Har Gobind Khorana

• Marshall Nirenberg

• Francis Crick

Answer 1

Har Gobind Khorana developed techniques for synthesizing RNA molecules with predetermined, repeated nucleotide sequences. This allowed scientists to create specific codons and determine which amino acid each codon specified. For example, repeated sequences like CUC UCU CUC UCU produced alternating amino acids, helping to decipher multiple codons.