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Which of the following was the very first restriction endonuclease to be isolated and characterized?

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Question

Which of the following was the very first restriction endonuclease to be isolated and characterized?

Options

  • EcoRI

  • Hind III

  • BamHI

  • Hind II

MCQ
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Solution

Hind II was the first restriction endonuclease to be isolated and characterized (five years after the 1963 breakthrough). It was isolated from the d-strain of Haemophilus influenzae and recognizes a specific six base-pair sequence.

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