Question

Which numerical abnormality is caused by failure of cytokinesis?

Options

• Monosomy

• Polyploidy

• Deletion

• Trisomy

Answer 1

Polyploidy results from failure of cytokinesis during cell division, leading to an increase in whole sets of chromosomes (3n, 4n, etc.). This is common in plants where it increases size and vigor. In animals, polyploidy is rare and usually lethal because dosage compensation mechanisms for multiple X chromosomes cannot function properly.