Question

Which immunoglobulin class is responsible for triggering hypersensitivity reactions in response to allergens?

Options

• IgE

• IgG

• IgM

• IgA

Answer 1

IgE is responsible for triggering hypersensitivity reactions, particularly Type I hypersensitivity (allergic reactions). When IgE antibodies bind to allergens, they interact with mast cells and basophils, causing the release of histamine and other chemical mediators that produce allergic symptoms.