Question

Which HPV strains are most commonly linked to cervical cancer?

Options

• HPV-16 and HPV-18

• All HPV strains cause cervical cancer equally

• HPV-1 and HPV-5

• HPV-6 and HPV-11 only

Answer 1

HPV-16 and HPV-18 are the high-risk strains most commonly linked to cervical cancer, as well as anal and throat cancers. These oncogenic strains produce viral proteins that inactivate tumor suppressors (p53 and Rb), leading to malignant transformation of epithelial cells.