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Which enzyme dissolves the hyaluronic acid between corona radiata cells and the zona pellucida?

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Question

Which enzyme dissolves the hyaluronic acid between corona radiata cells and the zona pellucida?

Options

  • Acrosin/Zona Lysin

  • Hyaluronidase (Sperm Lysin)

  • Corona Penetrating Enzyme (CPE)

  • Protease

MCQ
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Solution

Hyaluronidase, also called Sperm Lysin, targets hyaluronic acid between corona radiata cells and the zona pellucida, dissolving both the corona radiata and zona pellucida at the entry point.

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