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Question
When a purine is replaced by a pyrimidine in base-pair substitution process the phenomenon is termed as ______.
Options
transition
transversion
frameshift mutation
tautomerisation
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Solution
When a purine is replaced by a pyrimidine in base-pair substitution process the phenomenon is termed as transversion.
Explanation:
When a purine (adenine or guanine) is replaced by a pyrimidine (cytosine or thymine) or vice versa in a base-pair substitution mutation, this type of mutation is called a transversion. In contrast, a transition mutation occurs when a purine is replaced by another purine or a pyrimidine is replaced by another pyrimidine. Transversions can cause more significant changes in the DNA sequence and potentially lead to more pronounced effects on the organism's phenotype.
