Question

What structural feature connects the two heavy chains and two light chains in an antibody molecule together?

Options

• Ionic interactions

• Hydrogen bonds

• Peptide bonds

• Disulphide bonds

Answer 1

Disulphide bonds are the primary covalent bonds that link the two heavy chains and two light chains together in an antibody molecule. These disulphide bonds form between cysteine residues and provide structural stability to the Y-shaped antibody, with additional stabilization coming from non-covalent interactions.