Question

What pathological condition results from sickled RBCs adhering to blood vessel walls?

Options

• Increased oxygen transport

• Improved blood flow

• Vaso-occlusion leading to tissue damage

• Enhanced RBC flexibility

Answer 1

When sickled RBCs adhere to blood vessel walls, they cause vaso-occlusion (blockage of blood vessels), which restricts blood flow and leads to tissue damage. Additionally, sickled RBCs are fragile and rupture easily, resulting in haemolytic anaemia.