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Question
What is the total DNA content per nucleosome?
Options
Approximately 200 base pairs
Approximately 146 base pairs
Approximately 90 base pairs
Approximately 350 base pairs
MCQ
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Solution
The total DNA per nucleosome unit is approximately 200 base pairs, consisting of 146 base pairs wrapped around the histone octamer plus approximately 20–90 base pairs of linker DNA that connects to the next nucleosome. This repeating unit creates the characteristic 'beads-on-a-string' structure observed in chromatin.
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