Question

What is the total chromosome count in a typical nullisomy condition?

Options

• 44

• 45

• 47

• 46

Answer 1

Nullisomy (2n − 2) results in a total of 44 chromosomes in humans, representing the loss of both homologous chromosomes of a homologous pair. This condition is usually lethal as the loss of both copies of an entire chromosome set removes essential genes necessary for survival and normal development.