Question

What is the term used to describe the loss of one or more chromosomes due to nondisjunction?

Options

• Aneuploidy

• Polyploidy

• Nullisomy

• Euploidy

Answer 1

Aneuploidy refers to the gain or loss of one or more individual chromosomes due to nondisjunction during meiosis. This results in karyotypes of 2n ± 1, 2n ± 2, etc. Aneuploidy includes trisomy and monosomy conditions and typically causes severe developmental abnormalities. It differs from euploidy (polyploidy), which involves changes in entire chromosome sets.