Question

What is the primary function of H2 receptors?

Options

• Their stimulation triggers immune cell activation

• Their stimulation increases gastric acid secretion

• Their stimulation produces skin reactions

• Their stimulation causes respiratory symptoms

Answer 1

H2 receptors are present in the gastric mucosa and their stimulation increases gastric acid secretion. This is why some antihistamines are used to treat peptic ulcers and acid reflux by blocking H2 receptors. Unlike H1 receptors, which mediate allergic symptoms, H2 receptors play a regulatory role in the digestive system, making them important targets for treatment of gastric acid-related disorders.