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What is the key function of Sertoli cells in the seminiferous tubules?

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Question

What is the key function of Sertoli cells in the seminiferous tubules?

Options

  • To nourish developing germ cells and form the blood-testis barrier

  • To synthesize and secrete testosterone

  • To produce spermatozoa

  • To initiate meiosis in germ cells

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Solution

Sertoli cells line the wall of seminiferous tubules and function as nurse cells. They nourish and provide structural support to developing germ cells throughout spermatogenesis. Additionally, Sertoli cells form the blood-testis barrier, which protects developing sperm from immune attack, and secrete anti-Müllerian peptide (ABP) and inhibin in response to FSH stimulation.

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