Question

What is the final diameter of the supercoiled nucleoid in prokaryotes?

Options

• ~30 µm

• ~350 µm

• ~1100 µm

• ~2 µm

Answer 1

After the complete process of compaction including supercoiling with HU proteins, DNA gyrase, and topoisomerase I, the final diameter of the prokaryotic supercoiled nucleoid is approximately 2 micrometres, representing a ~550-fold compaction from the original 1100 micrometres.