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Question
What is anaphylactic shock?
Options
A severe acute emergency where a person develops shock after injection of a foreign protein due to sensitization from a previous dose
An immune deficiency disorder characterized by low antibody production
A mild allergic reaction with localized symptoms
A chronic progressive condition that develops slowly over years
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Solution
Anaphylactic shock is a severe acute emergency that occurs when a previously sensitized individual is exposed to a foreign protein again, even in small amounts. The prior exposure has created IgE antibodies bound to mast cells throughout the body. Upon re-exposure, massive simultaneous discharge of histamine and other mediators from mast cells occurs, causing systemic reactions including extreme hypotension, shock, and potentially death if not treated immediately with adrenaline.
