Question

What is a point mutation?

Options

• The exchange of genetic material between homologous chromosomes

• A change in the number of chromosomes in a cell

• A change in the nucleotide sequence of DNA at a single specific gene

• An increase in the dose of the entire genome

Answer 1

A gene or point mutation is defined as a change in the nucleotide sequence of DNA at a single specific gene. This type of mutation is distinct from chromosomal or genomic mutations and represents a discrete alteration in genetic coding.