Question

What energy molecules are required during translation?

Options

• ATP and GTP

• NADP and FADH2

• Only ATP

• Only GTP

Answer 1

Both ATP and GTP are required during translation. ATP is used in the amino acid activation step when aminoacyl-tRNA synthetase catalyzes the attachment of amino acids to tRNA. GTP is used as an energy source during various steps of translation including initiation, elongation (particularly in translocation), and termination. These nucleotide triphosphates provide the energy needed for the ribosome to function efficiently.