Question

What chromosomal abnormality characterizes Edward's syndrome?

Options

• Extra chromosome 13 causing multiple organ malformations

• Missing X chromosome causing short stature

• Extra chromosome 18 causing severe developmental defects

• Extra chromosome 21 causing intellectual disability

Answer 1

Edward's syndrome, or Trisomy 18, is characterized by the presence of an extra chromosome 18, resulting in severe developmental defects and multiple congenital anomalies. It is one of the major chromosomal abnormalities detectable through amniocentesis.