Question

What characteristic feature of tRNA nucleotides is especially common compared to other RNA molecules?

Options

• Methylated ribose sugars

• Unusual sugar-phosphate backbones

• Extra phosphate groups

• Modified bases

Answer 1

Modified bases are especially abundant in tRNA molecules compared to other RNA types. These modifications, including pseudouridine (Ψ), dihydrouridine (D), and inosine (I), are essential for proper tRNA folding, stability, and recognition by aminoacyl-tRNA synthetases and the ribosome during translation.