Question

What are the two primary mechanisms by which RNA interference regulates gene expression?

Options

• Chromatin remodeling and histone modification

• Epigenetic methylation and DNA repair

• Pre-transcriptional silencing and translational enhancement

• Transcriptional Gene Silencing (TGS) and Post-Transcriptional Gene Silencing (PTGS)

Answer 1

RNA interference limits gene expression through two mechanisms: Transcriptional Gene Silencing (TGS) which suppresses transcription directly, and Post-Transcriptional Gene Silencing (PTGS) which degrades RNA after it has been produced. Both mechanisms contribute to silencing gene expression at different levels.