Very Short Answer Question: Why are Okazaki fragments formed on lagging strand only? - Biology

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Very Short Answer Question:

Why are Okazaki fragments formed on lagging strand only?



  1. The two strands in DNA are antiparallel i.e. one strand runs in 5’ → 3’ direction whereas the other runs in 3’ → 5’.
  2. The DNA polymerase synthesizes a new DNA strand in 5’ → 3’ direction only.
  3. Leading template is synthesized continuously and lagging template is synthesized discontinuously.
  4. Due to 5’ → 3’ polymerizing activity of DNA polymerase Okazaki fragments are formed only on lagging strand only.
Concept: DNA Replication
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Chapter 4: Molecular Basis of Inheritance - Exercises [Page 92]


Balbharati Biology 12th Standard HSC for Maharashtra State Board
Chapter 4 Molecular Basis of Inheritance
Exercises | Q 2.5 | Page 92


_______ enzymes are used as biological scissors in r-DNA technology.

(A) Restriction endonucleases

(B) DNA ligases

(C) DNA polymerases

(D) Reverse transcriptases

Explain replication of bacteriophage with the help of a suitable diagram.

What is Bacteriophage?

As the base sequence present on one strand of DNA decides the base sequence of other strands; this strand is considered as ______.

Long Answer Question:

Explain the process of DNA replication.

Semiconservative mechanism of DNA was detected using:

How Meselson and Stahl explained the concept of Semiconservative Replication of DNA experimentally?

Okasaki fragments are joined together by ______.

What are Okazaki fragments?

E. coli cell grown on 15N medium are transferred to 14N medium and allowed to grow for two generations. DNA extracted from these cells is ultracentrifuged in a cesium chloride density gradient. What density distribution of DNA would you expect in this experiment?

What is the basis for the difference in the synthesis of the leading and lagging strand of DNA molecules?

Which of the following statements about DNA replication is not correct?

Which of the following statements is not true about DNA replication in eukaryotes?

Meselson and Stahl’s experiment proved ____________.

Differentiate - Leading stand and lagging strand.

From their examination of the structure of DNA, What did Watson and Crick infer about the probable mechanism of DNA replication, coding capability, and mutation?

a) Identify the figure given below

b) Redraw the structure as a replicating fork and label the parts

c) Write the source of energy for this replication and name the enzyme involved in this process.

d) Mention the differences in the synthesis of protein, based on the polarity of the two template strands.

Identify the direction of DNA replication in eukaryotes.

E. coli, in which both the strands of DNA are labeled with 15N is transferred to 14N medium and allowed to replicate for three generations. What would be the number of hybrid DNA molecules in the third generation?

Enzyme ______ brings about the DNA unwinding by breaking weak hydrogen bonds in the vicinity of origin.

In which direction polymerization of DNA nucleotides occurs during the synthesis of lagging strand?

At the point of origin, enzyme endonuclease nicks one of the strands of DNA by breaking the ______

Identify the CORRECT combination of statements with respect to DNA synthesis.

I. Always the direction of DNA polymerization 5' → 3' when referring to the polarity of strand being synthesized.

II. DNA ligase forms hydrogen bonds between two newly synthesized DNA strands.

III. DNA polymerases on their own cannot initiate the process of replication.

IV. DNA polymerase can catalyse polymerization in both 5'→ 3' and 3'→ 5' direction.

The addition of nucleotides on the lagging strand occurs ____________ during DNA replication.

In a segment of DNA with 10 base pairs, the numbers of sugar molecules are _________.

Nucleolus is a major center for:

"DNA is considered as genetic material" - Why?

Extension of the plasma membrane in a prokaryotic cell is ______.

Which of the following statement is incorrect?

Wobble position means:

Match the following column.

Column - I Column - II
(A) DNA structure 1. Muller and stadder
(B) Semiconservative replication of DNA 2. Beadle and partum
(C) One gene-one enzyme theory 3. Watson and crick
(D) Induction of mutation 4. Massillon and stahl

Okazaki is known for his contribution to the under tanding of:

During replication of DNA Okazaki fragments are formed in the direction:

Identify the biomolecule that is capable of self-replication.

Okazaki segments are formed during ______.

Which of the following reaction is required for proofreading during DNA replication by DNA polymerase III?

What background information did Watson and Crick had available with them for developing a model of DNA? What was their own contribution?

During the replication of DNA, the separated strands are prevented from recoiling by using ______.

Characteristics unique to DNA are ______.

Draw a suitable diagram of replication of eukaryotic DNA and label any three parts.

Torsional stress created during DNA replication is relieved by ______.

The sequence of nitrogenous bases on DNA molecule is ATCGA. Which of the following is the correct complementary sequence of nitrogenous bases on mRNA molecule?


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